# Astellas Pharma (4503.JP)

Canonical: https://gigainvestors.com/s/4503.JP

Analysis as of: 2026-10-15T07:10:20.046Z. Financial observations: FY2013–FY2026.

Listing currency: JPY. Reporting currency: JPY.

## Verdict

Not a wonderful business

Quality tests for Buy: not passed (profit record: pass; earnings resilience is evidence only). Published buy qualification: no.

Share price: JPY 2,356.50 per share; close as of 2026-10-15.

Estimated value: low JPY 1,450.46 per share, central JPY 1,937.56 per share, high JPY 2,248.60 per share. Buy at or below the central value JPY 1,937.56 per share. Valuation as of 2026-10-15T07:10:20.046Z; scenarios are not confidence intervals.

Expected annual return: 8.7% at the stated quote. About 8.7% a year at today's price (required return 10.0%). required return 10.0% a year (10% floor; JP 10-year bond 2.9% + 4 points).

## Checklist

### understandable: fail

- 4 revenue declines in the last 10 years (informational)

- operating margin variation exceeds 0.35

- Financial history: 10 years

- Years with declining revenue: 4

- Years with a net loss: 0

- Operating margin variation: 0.53×

Chart: Operating margin; fiscal year observations.

- FY2018: 0.16×

- FY2019: 0.19×

- FY2020: 0.19×

- FY2021: 0.11×

- FY2022: 0.12×

- FY2023: 0.09×

- FY2024: 0.02×

- FY2025: 0.02×

- FY2026: 0.18×

### moat: fail

- ROIC median below threshold

- ROIC worst years below threshold (more than 1 bad year allowed)

- ROIC, median of available years: 14.6%

- ROIC, second-lowest year: 2.4%

- Years with nonpositive capital: 0

- Capital spending / revenue: 5.1%

- ROIC including acquisitions, ten-year median: 9.4%

- Typical minus recent gross margin: -2.8 pp

Chart: ROIC excluding acquisitions; fiscal year observations.

- FY2018: 22.3%

- FY2019: 30.2%

- FY2020: 28.1%

- FY2021: 14.5%

- FY2022: 14.6%

- FY2023: 10.7%

- FY2024: 1.0%

- FY2025: 2.4%

- FY2026: 17.7%

### economics: pass

- Owner earnings / net income, 5-yr: 1.47×

- Cash conversion uses consolidated totals: No

- Owner earnings, five-year total: JPY 854B

- Net income, five-year total: JPY 582B

- Working capital / revenue, annual change: 1.3 pp

- Working capital / revenue, final three-year average: 7.4%

Chart: Annual owner cash / profit; fiscal year observations.

- FY2022: 0.88×

- FY2023: 1.01×

- FY2024: 4.64×

- FY2025: 3.54×

- FY2026: 1.32×

### management: fail

- Historical market-dollar context (not the management verdict): 2017 to 2026 (9 years)

- buybacks unrelated to price (informational)

- Per-share earnings: 89.75 to 28.35 (three-year endpoint medians)

- per-share value declined or ends nonpositive

- Management verdict uses per-share economic progress: Yes

- Ordinary dilution, 10-year annual growth: -1.8%

- Ordinary dilution, 5-year annual growth: -0.7%

- Market cap gain: JPY 1.42T

- Cumulative retained earnings: JPY 91B

- Diluted shares, 10-year annual growth: -1.8%

- Diluted shares, 5-year annual growth: -0.7%

- $1 test, starting fiscal year: FY2017

- $1 test, ending fiscal year: FY2026

- Per-share value growth: -13.4%

- Per-share value change: JPY -61.40

- Per-share value, starting three-year median: JPY 89.75

- Per-share value, ending three-year median: JPY 28.35

- Buybacks concentrated in cheaper years (correlation): -0.40

- Average buyback yield: 0.6%

- Buyback history: 4 years

- Debt-funded buybacks: No

- Cumulative net income, 10 years: JPY 1.50T

- ROIC, last three-year median: 2.4%

Chart: Earnings per share; fiscal year observations.

- FY2017: JPY 103.69

- FY2018: JPY 81.11

- FY2019: JPY 115.05

- FY2020: JPY 104.15

- FY2021: JPY 64.93

- FY2022: JPY 67.08

- FY2023: JPY 54.24

- FY2024: JPY 9.51

- FY2025: JPY 28.35

- FY2026: JPY 162.77

### accounting: pass

- Sloan accruals: -7.5%

- Restructuring years, last five: 0

- Stock compensation / operating cash flow: 0.0%

- Earnings backed by cash: Yes

- Operating cash / earnings: 1.92×

- Accounting red flags: 0

- Goodwill and intangibles / equity: 0.79×

Chart: Sloan accruals; fiscal year observations.

- FY2017: -0.9%

- FY2018: -8.0%

- FY2019: -1.9%

- FY2020: -1.1%

- FY2021: -8.2%

- FY2022: -5.7%

- FY2023: -9.3%

- FY2024: -4.4%

- FY2025: -4.3%

- FY2026: -7.5%

## Holders

## Price story

Price needs cash profits to grow 8.1% a year for ten years · sales +11.9%

Story as of 2026-10-16T10:00:14.176Z; price observation 2026-10-15.

Price needs cash profits to grow 8.1% a year for ten years

### Sales · FY2025–2026

sales +11.9%; source https://disclosure2dl.edinet-fsa.go.jp/searchdocument/pdf/S100YBPK.pdf; observed 2026-06-16.

- FY2017: JPY 1.31T 

- FY2018: JPY 1.30T 

- FY2019: JPY 1.31T 

- FY2020: JPY 1.30T 

- FY2021: JPY 1.25T 

- FY2022: JPY 1.30T 

- FY2023: JPY 1.52T 

- FY2024: JPY 1.60T 

- FY2025: JPY 1.91T 

- FY2026: JPY 2.14T 

### Gross margin · FY2026

gross margin 80.9%; source https://disclosure2dl.edinet-fsa.go.jp/searchdocument/pdf/S100YBPK.pdf; observed 2026-06-16.

- FY2018: 77.4% 

- FY2019: 77.6% 

- FY2020: 78.7% 

- FY2021: 80.3% 

- FY2022: 80.5% 

- FY2023: 81.0% 

- FY2024: 81.8% 

- FY2025: 81.7% 

- FY2026: 80.9% 

## Owner memo

Memo as of 2026-10-16T08:06:05.509Z.

### How it makes money

Annual sales are JPY 2.1 trillion.

- Source: https://disclosure2dl.edinet-fsa.go.jp/searchdocument/pdf/S100YBPK.pdf (filed 2026-06-16); FY2026: revenue 2139245000000; grossProfit 1730820000000; margin = grossProfit / revenue.

### Why customers stay

Margins ranged from 80.9% to 81.8% during 2024–26; it earns 14.6% on its capital.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); FY2024: grossProfit / revenue = 81.8%.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); FY2025: grossProfit / revenue = 81.7%.

- Source: https://disclosure2dl.edinet-fsa.go.jp/searchdocument/pdf/S100YBPK.pdf (filed 2026-06-16); FY2026: grossProfit / revenue = 80.9%.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); 10-year return on capital observations [[2018,0.22252266222100733],[2019,0.30182235781279276],[2020,0.2806092112525933],[2021,0.14548807612662762],[2022,0.14636640168529347],[2023,0.10694391436911918],[2024,0.009888479497837414],[2025,0.023570704071329537],[2026,0.17716320130109933]]; median 0.14636640168529347. ROIC follows the displayed moat series; financial companies use return on tangible equity.

### Can it raise prices

Kept about a 80% gross margin through 2022 cost inflation.

- Source: https://disclosure2dl.edinet-fsa.go.jp/searchdocument/pdf/S100YBPK.pdf (filed 2026-06-16); Gross margin observations: [[2021,0.8030752412110813],[2022,0.804801556594348],[2023,0.8101215643950194]]; range within 2 percentage points.

### Where the cash goes

Paid dividends in 4 of 9 years; bought back JPY 730 million of shares.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); FY2018: growth capex 0; upkeep 40285000000; owner earnings 189257000000. Growth capex / owner earnings = 0.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); FY2019: growth capex 0; upkeep 52128000000; owner earnings 233595000000. Growth capex / owner earnings = 0.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); FY2020: growth capex 0; upkeep 77888000000; owner earnings 166259000000. Growth capex / owner earnings = 0.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); FY2021: growth capex 0; upkeep 77441000000; owner earnings 99909000000. Growth capex / owner earnings = 0.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); FY2022: growth capex 0; upkeep 76448000000; cash acquisitions 670000000; owner earnings 109507000000. Growth capex plus acquisitions / owner earnings = 0.006118330335047074.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); FY2023: growth capex 0; upkeep 88541000000; cash acquisitions 0; owner earnings 99416000000. Growth capex plus acquisitions / owner earnings = 0.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); FY2024: growth capex 0; upkeep 82497000000; cash acquisitions 784974000000; owner earnings 79142000000. Growth capex plus acquisitions / owner earnings = 9.918551464456293.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); FY2025: growth capex 0; upkeep 57330000000; cash acquisitions 0; owner earnings 179470000000. Growth capex plus acquisitions / owner earnings = 0.

- Source: https://disclosure2dl.edinet-fsa.go.jp/searchdocument/pdf/S100YBPK.pdf (filed 2026-06-16); FY2026: growth capex 0; upkeep 84645000000; owner earnings 386008000000. Growth capex / owner earnings = 0.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); Dividend observations: [[2018,0],[2019,0],[2020,0],[2021,0],[2022,0],[2023,100355000000],[2024,116653000000],[2025,128993000000],[2026,136099000000]]. Zero only counted when supported by a complete cash-flow statement.

- Source: https://query2.finance.yahoo.com/ws/fundamentals-timeseries/v1/finance/timeseries/4503.T (filed 2026-06-16); FY2026: cash repurchases 730000000 JPY.

### What the price says

The price assumes cash profits grow 8.1% yearly over ten years.

- Source: https://eodhd.com/financial-apis/stock-etfs-fundamental-data-feeds/ (filed 2026-06-16); Ten-year compound average after fade. Initial solved rate 0.10296704462107698. Price 2356.5; FX 1; discount 0.1; same standard ten-year fade to terminal 0.03.  Closing-price date 2026-10-15.

## Monthly share-price history (JPY per share)

- 2016-11: JPY 1,579.50 per share

- 2016-12: JPY 1,623.50 per share

- 2017-01: JPY 1,513.50 per share

- 2017-02: JPY 1,512.00 per share

- 2017-03: JPY 1,466.00 per share

- 2017-04: JPY 1,468.00 per share

- 2017-05: JPY 1,398.50 per share

- 2017-06: JPY 1,374.50 per share

- 2017-07: JPY 1,408.00 per share

- 2017-08: JPY 1,383.50 per share

- 2017-09: JPY 1,431.50 per share

- 2017-10: JPY 1,508.50 per share

- 2017-11: JPY 1,426.00 per share

- 2017-12: JPY 1,437.00 per share

- 2018-01: JPY 1,440.00 per share

- 2018-02: JPY 1,580.50 per share

- 2018-03: JPY 1,614.00 per share

- 2018-04: JPY 1,605.50 per share

- 2018-05: JPY 1,664.50 per share

- 2018-06: JPY 1,689.00 per share

- 2018-07: JPY 1,817.50 per share

- 2018-08: JPY 1,882.00 per share

- 2018-09: JPY 1,982.00 per share

- 2018-10: JPY 1,747.00 per share

- 2018-11: JPY 1,744.50 per share

- 2018-12: JPY 1,401.50 per share

- 2019-01: JPY 1,609.50 per share

- 2019-02: JPY 1,718.50 per share

- 2019-03: JPY 1,658.50 per share

- 2019-04: JPY 1,509.00 per share

- 2019-05: JPY 1,462.50 per share

- 2019-06: JPY 1,535.00 per share

- 2019-07: JPY 1,553.50 per share

- 2019-08: JPY 1,472.00 per share

- 2019-09: JPY 1,538.50 per share

- 2019-10: JPY 1,858.50 per share

- 2019-11: JPY 1,867.50 per share

- 2019-12: JPY 1,870.00 per share

- 2020-01: JPY 1,950.50 per share

- 2020-02: JPY 1,699.00 per share

- 2020-03: JPY 1,671.00 per share

- 2020-04: JPY 1,786.50 per share

- 2020-05: JPY 1,914.50 per share

- 2020-06: JPY 1,799.50 per share

- 2020-07: JPY 1,650.00 per share

- 2020-08: JPY 1,664.50 per share

- 2020-09: JPY 1,567.00 per share

- 2020-10: JPY 1,435.00 per share

- 2020-11: JPY 1,483.50 per share

- 2020-12: JPY 1,594.00 per share

- 2021-01: JPY 1,692.50 per share

- 2021-02: JPY 1,674.00 per share

- 2021-03: JPY 1,702.00 per share

- 2021-04: JPY 1,640.50 per share

- 2021-05: JPY 1,797.50 per share

- 2021-06: JPY 1,934.50 per share

- 2021-07: JPY 1,739.00 per share

- 2021-08: JPY 1,857.00 per share

- 2021-09: JPY 1,842.50 per share

- 2021-10: JPY 1,917.00 per share

- 2021-11: JPY 1,779.50 per share

- 2021-12: JPY 1,870.50 per share

- 2022-01: JPY 1,850.50 per share

- 2022-02: JPY 1,918.50 per share

- 2022-03: JPY 1,911.00 per share

- 2022-04: JPY 1,978.00 per share

- 2022-05: JPY 2,062.50 per share

- 2022-06: JPY 2,115.00 per share

- 2022-07: JPY 2,087.50 per share

- 2022-08: JPY 1,984.50 per share

- 2022-09: JPY 1,917.00 per share

- 2022-10: JPY 2,046.50 per share

- 2022-11: JPY 2,128.00 per share

- 2022-12: JPY 2,006.50 per share

- 2023-01: JPY 1,912.50 per share

- 2023-02: JPY 1,919.00 per share

- 2023-03: JPY 1,883.00 per share

- 2023-04: JPY 2,048.00 per share

- 2023-05: JPY 2,207.50 per share

- 2023-06: JPY 2,149.00 per share

- 2023-07: JPY 2,080.50 per share

- 2023-08: JPY 2,214.50 per share

- 2023-09: JPY 2,074.00 per share

- 2023-10: JPY 1,900.00 per share

- 2023-11: JPY 1,797.50 per share

- 2023-12: JPY 1,686.00 per share

- 2024-01: JPY 1,725.00 per share

- 2024-02: JPY 1,651.50 per share

- 2024-03: JPY 1,645.00 per share

- 2024-04: JPY 1,514.00 per share

- 2024-05: JPY 1,548.50 per share

- 2024-06: JPY 1,590.00 per share

- 2024-07: JPY 1,747.50 per share

- 2024-08: JPY 1,817.00 per share

- 2024-09: JPY 1,647.00 per share

- 2024-10: JPY 1,795.50 per share

- 2024-11: JPY 1,561.50 per share

- 2024-12: JPY 1,534.50 per share

- 2025-01: JPY 1,514.50 per share

- 2025-02: JPY 1,454.00 per share

- 2025-03: JPY 1,446.50 per share

- 2025-04: JPY 1,427.50 per share

- 2025-05: JPY 1,429.00 per share

- 2025-06: JPY 1,416.50 per share

- 2025-07: JPY 1,578.50 per share

- 2025-08: JPY 1,620.00 per share

- 2025-09: JPY 1,600.50 per share

- 2025-10: JPY 1,613.50 per share

- 2025-11: JPY 1,969.00 per share

- 2025-12: JPY 2,093.00 per share

- 2026-01: JPY 2,144.00 per share

- 2026-02: JPY 2,601.50 per share

- 2026-03: JPY 2,519.00 per share

- 2026-04: JPY 2,232.00 per share

- 2026-05: JPY 2,283.00 per share

- 2026-06: JPY 2,175.00 per share

- 2026-07: JPY 2,202.00 per share

- 2026-08: JPY 2,371.50 per share

- 2026-09: JPY 2,320.50 per share

- 2026-10: JPY 2,258.50 per share

## Annual estimated value (JPY per share)

- FY2022: low JPY 1,135.66 per share, central JPY 1,270.63 per share, high JPY 1,450.29 per share

- FY2023: low JPY 1,120.87 per share, central JPY 1,479.76 per share, high JPY 1,702.86 per share

- FY2024: low JPY 1,086.40 per share, central JPY 1,402.13 per share, high JPY 1,613.36 per share

- FY2025: low JPY 1,201.31 per share, central JPY 1,618.07 per share, high JPY 1,882.75 per share

- FY2026: low JPY 1,450.46 per share, central JPY 1,937.56 per share, high JPY 2,248.60 per share

Historical values use today's bond yield for every fiscal year

Historical values use today's FX rate into trading currency for every fiscal year

Historical values use current restated fundamentals and current commodity classification; they are not point-in-time estimates

Prior published observations retained from 2026-10-15T07:10:20.046Z where newer inputs omit a numeric field or fiscal period.

## Sources

[Original EDINET filing](https://disclosure2dl.edinet-fsa.go.jp/searchdocument/pdf/S100YBPK.pdf); period 2026-03-31, filed 2026-06-16.

Estimates depend on assumptions and are not guarantees or investment advice. Underlying data remains subject to its source licenses; public reading does not grant bulk redistribution rights.
← Companies

Astellas Pharma

4503 · JP

Nikkei 225 · TOPIX Large70

Not a wonderful business

2 quality tests fail. A lower price would not fix the business.

Share price
JPY 2,356.50
Buy up to
JPY 1,937.56
Expected / yr
8.7% at today's price (10.0% at central value)

The business

How it makes money
Why customers stay
Can it raise prices
Where the cash goes
What the price says

1. Is this a good business?

Evidence only; not required for Buy

Margins varied 53.2% around their average (limit 35%).

9y median
12.0%
Worst year
1.6%
Latest · 2026
17.9%

Capital return excluding acquisitions: median 14.6% (minimum 15%), and the second-worst year 2.4% (minimum 10%).

9y median
14.6%
Worst year
1.0%
Latest · 2026
17.7%

Each $1 of profit left $1.47 for owners over five years (minimum $0.80).

Five-year totals
1.47×
Annual median
1.32×
Latest · 2026
1.32×

Per-share value fell from 89.75 to 28.35, comparing three-year medians at each end (must rise and stay positive).

10y median
JPY 74.10
Worst year
JPY 9.51
Latest · 2026
JPY 162.77

Profits were backed by cash: accruals were -7.5% of assets (limit 10%).

10y median
-5.0%
Worst year
-0.9%
Latest · 2026
-7.5%

Profit record · pass 0 loss years in 10 (at most 2), mean operating margin 11.9%, three-year average owner earnings per share 119.98 JPY.

2. Is the price low enough?

Price & return math
Value rangeJPY 1,450.46 – JPY 2,248.60
Buy at or belowCentral value JPY 1,937.56
Discount to value1 − 2356.50 / 1937.56 = -21.6%
Return / yearAbout 8.7% a year at today's price (required return 10.0%)
Cash-flow inputsOwner cash JPY 100.91/share; 6.5% growth for 5 years, then fades to 3.0%; excess cash JPY 133.34/share today.
Required return10.0% / year, earned by construction at the central value
RevenueJPY 2.14T
2.14T020172026
FY2017 · Revenue: JPY 1.31T; FY2018 · Revenue: JPY 1.30T; FY2019 · Revenue: JPY 1.31T; FY2020 · Revenue: JPY 1.30T; FY2021 · Revenue: JPY 1.25T; FY2022 · Revenue: JPY 1.30T; FY2023 · Revenue: JPY 1.52T; FY2024 · Revenue: JPY 1.60T; FY2025 · Revenue: JPY 1.91T; FY2026 · Revenue: JPY 2.14T
Revenue
Owner earningsJPY 386B
386B020172026
FY2018 · Owner earnings: JPY 189B; FY2019 · Owner earnings: JPY 234B; FY2020 · Owner earnings: JPY 166B; FY2021 · Owner earnings: JPY 100B; FY2022 · Owner earnings: JPY 110B; FY2023 · Owner earnings: JPY 99B; FY2024 · Owner earnings: JPY 79B; FY2025 · Owner earnings: JPY 179B; FY2026 · Owner earnings: JPY 386B
Owner earnings
Operating margin17.9%
18.8%0.0%20172026
FY2018 · Operating margin: 16.4%; FY2019 · Operating margin: 18.7%; FY2020 · Operating margin: 18.8%; FY2021 · Operating margin: 10.9%; FY2022 · Operating margin: 12.0%; FY2023 · Operating margin: 8.8%; FY2024 · Operating margin: 1.6%; FY2025 · Operating margin: 2.1%; FY2026 · Operating margin: 17.9%
Operating margin
Net cash / debtJPY -284B
332B-643B20172026
FY2018 · Net cash / debt: JPY 332B; FY2019 · Net cash / debt: JPY 311B; FY2020 · Net cash / debt: JPY 318B; FY2021 · Net cash / debt: JPY 326B; FY2022 · Net cash / debt: JPY 316B; FY2023 · Net cash / debt: JPY 252B; FY2024 · Net cash / debt: JPY -584B; FY2025 · Net cash / debt: JPY -643B; FY2026 · Net cash / debt: JPY -284B
Net cash / debt
Diluted shares1.8B
2.1B020172026
FY2017 · Diluted shares: 2.1B; FY2018 · Diluted shares: 2.0B; FY2019 · Diluted shares: 1.9B; FY2020 · Diluted shares: 1.9B; FY2021 · Diluted shares: 1.9B; FY2022 · Diluted shares: 1.8B; FY2023 · Diluted shares: 1.8B; FY2024 · Diluted shares: 1.8B; FY2025 · Diluted shares: 1.8B; FY2026 · Diluted shares: 1.8B
Diluted shares
Prices 15 Oct 2026 · FY2026Original filing ↗ ·